墨白 Rejuran PN (Rejuran Healer) is often hailed as the “Hermès of injectable skincare,” and it ranks among the most popular regenerative injections in South Korea’s Dermatology clinics. What’s it like to get Rejuran treatment at a PFK (Dermatology clinic) in Busan? Is it painful? How long do the results last? How many days does it take to recover? This article offers a firsthand perspective, detailing the entire process of receiving Rejuran PN treatments at clinics in Busan, including observations on the results and key post-treatment care tips, to help you decide whether it’s worth giving it a try.
I. What is Rejuran PN?
Rejuran is a skin regeneration injection developed by PharmaResearch in South Korea. Its key ingredient is PN (polynucleotide), which are DNA fragments extracted and refined from salmon reproductive cells. PN exhibits high compatibility with human tissues, resulting in minimal immune reactions and side effects. The classic Healer black-box version contains 2
What sets it apart from traditional hyaluronic acid injections is that while regular hyaluronic acid injections simply “hydrate the skin,” Rejuran helps the skin learn to hydrate on its own. Once PN penetrates the dermal layer, it stimulates fibroblasts, promoting the production of Collagen and elastin, thereby improving skin quality at its core. Clinical data shows that it can reduce fine lines around the eyes by 94.29
In addition to the classic Healer in black box packaging, the Rejuran series also includes the I series (specifically formulated for the eye area), HB/HB+ (a pain-relieving version containing Filler and lidocaine), and the S series (high-viscosity formula for scars and acne pits). For a more detailed comparison of these products, check out our comprehensive review of the 7 top-selling injectable fillers.
II. Why Choose Busan PFK for Rejuran Treatment?
As the second-largest city in South Korea and a major hub for medical aesthetics, Busan offers more affordable prices for Rejuran products compared to Gangnam in Seoul. Take JRYN Dermatology as an example – the Rejuran Healer 1 centum core starts at just ₩100,000 (approximately NT$2,450), whereas similar treatments in Gangnam, Seoul typically start at ₩150,000. According to the comprehensive pricing list for fillers in South Korea, treatment costs for regeneration-based fillers in Busan are generally 20
Furthermore, the PFK Clinic in Busan is equipped with facilities that are on par with those in Seoul. We’ve conducted a detailed comparison of medical aesthetics services between Busan and Seoul, analyzing the differences between the two cities. In the Seomyeon business district of Busan, there are several large-scale Dermatology clinics such as JRYN, ToxNFill, and The First, all of which offer Rejuran’s full range of products and provide consultation services in Chinese.
III. Who is Rejuran PN suitable for?
| Ideal for | Who Should Avoid It |
|---|---|
| Those troubled by fine lines and dry lines | Deep Nasolabial Fold Correction (requires Filler injection) |
| rough, dull, and lifeless skin texture | Severe pigmentation (requires laser treatment/whitening) |
| Declining skin elasticity, sagging signs of aging | Sunken acne scars (requiring subcision or fractional laser treatment) |
| Weak skin around the eyes with noticeable fine lines | People allergic to salmon |
| Looking to improve overall skin quality rather than achieve localized shaping | Patients with keloid-prone skin or autoimmune diseases |
| The post-surgery recovery period requires accelerated healing | Pregnancy and breastfeeding (consult a doctor first) |
If you’re not sure whether Rejuran is right for you, you can start by checking out the in-person consultation recommendations from top Dermatology clinics in their Rejuran comparison reviews, or learn about the differences between Juvelook and Rejuran to help make your decision.
IV. The Actual Consultation Process for Rejuran at Busan PFK
Step 1: Make an online appointment
Before you go, make an appointment at a Dermatology clinic in Busan through the BeautsGO APP or mini-program. Search for “Busan” and select a partner clinic. When booking, mention that you need a consultation in Chinese and would like to receive Rejuran PN injections. Simply provide your name, contact information, number of people attending, and preferred time slot. You can also refer to guides on getting hyaluronic acid injections in South Korea for more details on making appointments.
Step 2: Visit the clinic for a face-to-face consultation
Upon arriving at the clinic, a Chinese-speaking customer service representative will assist you in filling out the consultation form. The doctor will use a skin analysis device to assess your skin condition—collecting data on moisture levels, elasticity, Pores, pigmentation, and more. Based on these findings, they will recommend the appropriate dosage (usually 1–2 centum core for the entire face) and determine if additional treatments are needed. Be sure to inform the doctor of any past allergies and medications you are currently taking during the consultation.
Step 3: Anesthesia and Injection
Apply an anesthetic cream about 20-30 minutes before the injection. Rejuran PN uses multiple injections in the dermal layer, requiring approximately 30-50 injection sites across the face. The amount of fluid injected at each site is very small (about 0.02-0.05 centum core), but discomfort from the needles is still noticeable—there may be slight stinging and a feeling of swelling, especially in areas with thinner subcutaneous tissue such as the Forehead and cheekbones. The entire procedure takes around 15-20 minutes.
If you’re particularly sensitive to pain, you might consider Rejuran HB Plus. This product contains lidocaine, an anesthetic ingredient, and studies show it can reduce pain by up to 56
Step 4: Immediate post-operative condition
After the treatment, the entire face will develop numerous small bumps (resembling mosquito bites). These are temporary elevations caused by the medication in the dermal layer, and they’re a normal reaction. The nurse will apply a soothing repair cream and apply ice compresses for 15 minutes. At this point, the face may appear a bit uneven, but there’s no need to worry—these bumps will subside within 1–3 days.
Step 5: Post-operative Care
The doctor will provide detailed post-surgery care instructions: avoid alcohol, saunas, and strenuous exercise on the day of the procedure; take strict sun protection measures to prevent pigmentation; keep the skin well-hydrated; and quit smoking and drinking. You can generally return to work the next day, but those prone to bruising are advised to avoid important appointments. For more details on post-surgery care, refer to the comprehensive guide on hyaluronic acid injections.
V. Observing the Effects of Rejuran and the Recovery Period
| Key time points | Skin condition | Important Notes |
|---|---|---|
| On the day of injection | Small bumps all over the face, mild redness | Apply ice packs for soothing effects and avoid getting it wet |
| Days 1–3 | The petechiae gradually fade, with possible mild bruising. | Enhance hydration and provide strong sun protection |
| Week 1 | The bruising fades, and the skin texture begins to become smoother. | Normal skincare and makeup are possible |
| Weeks 2–4 | Collagen begins to proliferate, reducing fine lines. | The results are gradually becoming visible. |
| Months 1-2 | Significant Lifting of skin elasticity with improved glow | Peak Effect Period |
| Months 3–6 | Long-lasting results with gradual metabolism | It’s recommended to get a follow-up injection to maintain the effect. |
The effects of Rejuran are gradual, unlike Filler injections that provide immediate contouring results. Over the course of several weeks after treatment, as Collagen is produced, the quality of the skin improves steadily. It’s recommended to receive injections every 2–4 weeks, with 3–4 sessions constituting a basic treatment course. Subsequent maintenance injections every 3–6 months are needed to achieve the best outcomes.
VI. Price Reference for Rejuran in Busan
| Project | Ideal for | Benefits | Recovery period | South Korean Won (₩) | New Taiwan Dollar (NT$) |
|---|---|---|---|---|---|
| Rejuran Healer 1 centum core | Reduce fine lines and improve skin texture | PN Regeneration, Collagen Proliferation | 1-3 days | Starting from ₩100,000 | Starting from NT$2,450 |
| Rejuran Healer 2 centum core | Full-face treatment | Full Face Regeneration & Repair | 1-3 days | Starting from ₩180,000 | Starting from NT$4,410 |
| Rejuran HB Plus 1 centum core | Pain-sensitive individuals | 56 | 1-3 days | Starting from ₩150,000 | Starting from NT$3,670 |
| Rejuran Seoul I (Eye Area) 1 centum core | Fine lines around the eyes | Special formula for the eye area | 1-3 days | Starting from ₩100,000 | Starting from NT$2,450 |
| Rejuran Glow Injection 1 centum core | Basic Moisturizing & Regeneration | PN+ Hyaluronic Acid Dual Action Treatment | 1-3 days | Starting from ₩40,000 | Starting from NT$980 |
The prices listed above are reference starting rates for Dermatology clinics in Busan; the actual cost will depend on the examination conducted on-site. Since Rejuran requires 3–4 sessions of foundational treatment followed by regular maintenance, it’s recommended to estimate the total cost rather than focusing solely on the price per session. For more detailed pricing information, you can check comparisons between the costs of hyaluronic acid injections in South Korea and those in other regions.
VII. Honest Reviews of Rejuran: Positive Feedback and Things to Keep in Mind
High praise everywhere
- Significant improvement in skin texture: After completing one treatment course, the skin truly becomes smoother and finer, with Pores appearing visually reduced.
- Reducing fine lines: Visible improvements are seen most notably in the dry lines around the eyes and Forehead, with no more powder buildup when smiling
- Short recovery time: You can return to work normally by the 3rd day, with no impact on your schedule
- Long-lasting results: While regular hyaluronic acid injections last about 1 month, Rejuran can provide effects that last 3 to 6 months.
- Busan offers great value for money: For the same products and services, it’s about 40
Keep in mind
- Some pain is expected: The traditional black-box injection method does cause discomfort, so those who are sensitive to pain are advised to choose the HB Plus version with numbing agents.
- Visible postoperative pits: The face appears uneven on the day of treatment, requiring 1–2 days to recover.
- Results are not immediate: Unlike Filler, which shows effects right away, it takes 2–4 weeks for results to gradually become apparent.
- Multiple sessions required: The effect of a single session is limited; it’s recommended to undergo at least 3 sessions for a complete treatment course.
- Risk of bruising: People with a tendency to bruise easily may take 1–2 weeks for the bruises to fully fade.
VIII. Rejuran vs Other Regeneration Needles: A Comparison
| Comparison Items | Rejuran PN | Juvelook | Asce+ Exosomes |
|---|---|---|---|
| Key Ingredients | PN (polynucleotide) | PDLLA (polylactic acid) | Stem Cell Culture Medium |
| Mechanism of Action | Stimulates collagen + repairs DNA | Stimulate collagen proliferation | Repair of cellular signal transduction |
| Ideal for | Reduce fine lines and improve skin texture | Pores and dull skin texture | Sensitive skin, damaged skin repair |
| Price (1 centum core) | Starting from ₩100,000 | Starting from ₩70,000 | In-person consultation required for quote |
| Long-lasting results | 3-6 months | 3-6 months | 2-3 months |
| Pain sensation | Medium (with pain-relief version) | Mild | Mild |
To learn more about the differences between these products, check out our in-depth review of Juvelook Black Bottle’s effects and a comprehensive breakdown of its prices.
IX. How to Book a Appointment at Rejuran BeautsGO in Busan
It’s extremely convenient to schedule Rejuran injections at Dermatology clinics in Busan through BeautsGO. You can first download the BeautsGO app, or simply search for and use the “BeautsGO” mini-program on WeChat. Enter “Busan” in the search bar to browse all partner clinics in the area, where you can view detailed prices for services like Rejuran, information about the doctors, and genuine customer reviews. Once you’ve made your choice, click “Schedule a Consultation” or “Book Now” at the bottom right, fill in your name, contact details, number of people attending, and preferred time slot, and submit the request. If you have any questions, you can always reach out to the platform’s Chinese-speaking customer service or via the WeChat official account “BeautsGO彼此美APP”. This not only ensures transparency in pricing but also helps avoid last-minute price hikes. The platform is also available to assist with post-service inquiries, making it highly convenient for travelers on independent trips.
BeautsGO Busan Cosmetology Appointment Booking
BeautsGO 認證
📍 Clinics located in various shopping areas such as Seomyeon and Haeundae in
Busan
🚇 Book appointments in Chinese · No need for Korean comm
unication
🕐 Full support from Chinese-speaking customer service staff
| Transparent pricing to avoid last-minute price hikes | ✓ Protection guaranteed |
| Chinese customer service provides full follow-up support | ✓ Thoughtful service |
| Post-surgery after-sales support available | ✓ Peace of mind |
* Search for “Busan” to browse all partner clinics in the Busan area.
X. Pre- and Post-Surgery Tips for Rejuran
Preoperative Preparation
- Stop taking medications or supplements that promote blood circulation, such as aspirin, vitamin E, and Omega-3, one week before the procedure.
- Those taking anticoagulant drugs must never stop taking them on their own; they should consult their treating physician first.
- Those allergic to salmon must inform the medical staff before the procedure.
- Avoid alcohol and spicy foods the day before the procedure
- Avoid wearing makeup on the day of the procedure and keep your face clean.
Post-surgery care
- Avoid alcohol, saunas, and intense exercise on that day
- Use strong sun protection (SPF 50+) to prevent pigmentation.
- Keep your skin well-hydrated by using gentle, restorative skincare products.
- Avoid contact with water and makeup within 24 hours after the procedure
- Avoid exfoliation and acid-based products for 1 week after the procedure
- Quit smoking and drinking, and get enough sleep.
XI. Frequently Asked Questions (FAQ)
Q1: Does one treatment of Rejuran PN work immediately?
It’s difficult to notice significant effects from a single injection. Rejuran works in a gradual manner — once it reaches the dermal layer, it takes several weeks to stimulate Collagen production. It’s recommended to get injections every 2–4 weeks, with 3–4 sessions constituting a basic treatment course. Results will start to become apparent after the second injection.
Q2: Is Rejuran PN really that painful?
There is some pain, but it’s tolerable. Rejuran requires multiple injections into the dermal layer, causing stinging and a feeling of swelling. An anesthetic cream is applied before the procedure to ease the discomfort. For those who are particularly sensitive to pain, Rejuran HB Plus, which contains lidocaine, can be chosen—reports suggest it reduces pain by 56
Q3: What’s the difference between Rejuran and hyaluronic acid injections?
The main component of regular hyaluronic acid injections is Filler, which works by “directly delivering moisture” to the skin, with effects lasting around 1 month. Rejuran, on the other hand, contains PN (polynucleotides) as its key ingredient, functioning to “stimulate the skin’s natural regeneration,” and its benefits in improving skin quality can last from 3 to 6 months. The two can be used together—first applying Rejuran to promote regeneration, followed by hyaluronic acid injections to enhance moisture supply.
Q4: How much cheaper is getting Rejuran treatments in Busan compared to Taiwan?
Taking Rejuran Healer 1 centum core as an example, the reference price in Busan starts at ₩100,000 (around NT$2,450). In Taiwan, similar treatments usually cost between NT$4,000 and NT$6,000. The price in Busan is roughly 40
Q5: Can Rejuran be used together with other treatments?
Sure. Common pairing options for Rejuran include: Botox (applying Botox first followed by Rejuran), Pico laser (can be done on the same day), and Thermage/HIFU (it’s recommended to wait at least 1 week between treatments). However, it’s not advised to use it together with Filler injections in the same area on the same day, as this may affect the dispersion of the medication. For specific treatment combinations, it’s best to consult a doctor in person.
Q6: Are there any side effects of Rejuran?
Rejuran has relatively few side effects, and PN exhibits high compatibility with human tissues. Common post-procedure reactions include papules (which subside within 1–3 days), mild swelling (which fades within 1–3 days), and bruising (which resolves over 1–2 weeks). Allergic reactions occur in very rare cases, so it is contraindicated for those allergic to salmon. It’s crucial to choose a reputable medical facility that uses authentic products.
XII. Related Reading Recommendations
Looking to learn more about Rejuran and medical aesthetics in South Korea? Here are some articles we recommend:
- Which hospitals in South Korea are highly recommended for Rejuran treatments? A comprehensive review of the top 4 Dermatology clinics in 2026
- Top Recommendations for Hyaluronic Acid Injection Products in South Korea! A Comprehensive Comparison of the 7 Most Popular Options in 2026
- Guide to Getting Hyaluronic Acid Injections in South Korea｜Comprehensive 2026 Guide
- Price Comparison: Water Injection Treatments in South Korea vs. Domestic Options | Complete Cost Breakdown for 2026
- How effective is the Juvelook Black Bottle? A comprehensive 2026 review
- Top Dermatology Treatments You Should Try in Busan! 5 Most Cost-Effective Procedures of 2026
