In recent years, the trend of medical aesthetics in South Korea has swept across Asia, and one brand name that keeps appearing frequently in this industry is Rejuran. Whether in Dermatology clinics in Myeongdong or medical aesthetics centers in Taiwan and Japan, Rejuran’s hyaluronic acid injections have almost become synonymous with “high-end skin regeneration.” So, what kind of brand is Rejuran exactly? Why is it dubbed the “Hermès among hyaluronic acid injections”? This article will provide you with a comprehensive and in-depth analysis covering everything from the brand’s background and technical advantages to its product lines and price range.
I. Background of the Rejuran brand: A flagship product from a leading biopharmaceutical group in South Korea
Rejuran is the flagship beauty and dermatology brand under South Korea’s PHARMA RESEARCH Group. PHARMA RESEARCH is a biopharmaceutical company listed in South Korea, specializing in regenerative medicine. With over 20 years of research and development experience, the group offers a range of medical-grade skin regeneration products.
Unlike ordinary skincare brands, Rejuran was never positioned as a “cosmetic” from the start—it is designed as a medical-grade skin regeneration agent. Its key ingredient, PDRN (Polydeoxyribonucleotides), derived from DNA fragments in salmon sperm and eggs, can penetrate deep into the dermis to activate cell repair and promote Collagen synthesis. It is a genuine biotech-based ingredient used in medical aesthetics.
For this very reason, Rejuran is classified as a prescription-grade cosmetic treatment in South Korea. It can only be administered through injections by licensed physicians at reputable Dermatology clinics or medical beauty centers—far beyond the category of ordinary skincare products.

II. What tier is Rejuran? A top-tier luxury brand in the medical aesthetics industry
If we were to classify medical beauty products by “tier,” Rejuran undoubtedly belongs to the category of high-end luxury brands. The following aspects clearly illustrate its premium positioning:
1. High technical barriers
Rejuran utilizes PDRN technology, which requires the extraction of DNA fragments with specific molecular weights from salmon sperm and eggs. The purification process is highly complex, resulting in extremely high production costs. Only a handful of manufacturers worldwide are capable of producing such ingredients in compliance with regulations. Moreover, Rejuran holds multiple core patents that make it difficult for competitors to replicate its technology.
2. Fully clinically certified
Rejuran has not only received approval from the MFDS (South Korea’s Food and Drug Safety Administration) in South Korea, but its various products have also earned EU CE certification as well as medical approvals in multiple Asian countries. Such high-level certifications represent a major barrier that countless fake products on the market are unable to overcome.
3. Brand Influence
Rejuran is one of the most widely used hyaluronic acid injection products in Dermatology clinics across South Korea. Top-tier Dermatology clinics in Gangnam, Seoul, almost all offer Rejuran treatment programs. Meanwhile, it has also become the “secret weapon” recognized by numerous Korean celebrities and internet influencers for maintaining optimal skin condition, earning it an extremely high reputation among consumers.

III. In-Depth Look at the Full Range of Rejuran Products: The Best Choices for Different Skin Types
Rejuran currently offers four major series, each targeting different skin concerns to create a comprehensive portfolio of high-end cosmetic treatments.

Rejuran PN (Healer)
The classic flagship series delivers deep hydration, anti-aging repair, and thickening of the stratum corneum to activate the skin’s natural healing mechanisms. Ideal for those over 30 who are looking to combat aging.

Rejuran HB (HB Plus)
Enhanced version with twice the potency of Black Box—helps repair aging skin, fade lip lines, and effectively restore damaged skin barriers. Ideal for those suffering from persistent redness and compromised skin barriers.

Rejuran Blue Box/Salmon (SWOMAN)
Restoration version – designed to address acne pits and scars, improve acne-prone skin, and tighten the complexion, effectively reducing skin unevenness. Ideal for those with acne-prone skin or scars.

IRejuran 1cc (regeneration, fine wrinkle improvement) (I)
A specialized version for the eye area, designed to fade fine lines, reduce Dark circle treatment, and fill in Tear trough correction — crafted specifically for delicate skin around the eyes. Ideal for those struggling with eye-related concerns.
| Series Name | Official Model | Key Benefits | Suitable for certain demographics |
|---|---|---|---|
| Rejuran PN (Healer) | REJURAN Healer | Deep hydration, anti-aging, repair of damaged skin tissue, thickening of the stratum corneum | Those over 30 seeking anti-aging solutions |
| Rejuran HB (HB Plus) | REJURAN HB Plus | Its efficacy is 2 times that of a “black box” product—it repairs aging skin and fades lip lines. | Those with damaged skin barrier and chronic redness |
| Rejuran Blue Box/Salmon (SWOMAN) | REJURAN S | Repair acne pits and scars, improve acne-prone skin, and tighten the complexion | Those struggling with acne-prone skin and acne scars |
| IRejuran 1cc (regeneration, fine wrinkle improvement) (I) | REJURAN I | Reduce fine lines around the eyes, eliminate Dark circle treatment, and fill in Tear trough correction | Those struggling with eye area concerns |
IV. Rejuran’s Price Positioning: High-end medical aesthetics where you get what you pay for
The premium positioning of Rejuran is naturally reflected in its price. As it is a medical-grade injection product, treatments must be conducted at authorized cosmetic clinics. Below are the approximate reference prices for various series (based on current rates at clinics in South Korea):
- Rejuran PN (Healer) Glow Injection: Starting at 150,000 KRW (prices may vary depending on the number of sessions and the clinic).
- Rejuran HB Plus Enhanced Version: Starting from 200,000 KRW
- Rejuran Blue Box/Salmon (SWOMAN) Repair Version: Starting at 180,000 KRW
- Seoul I IRejuran 1cc (regeneration, fine wrinkle improvement) Eye Area Version: Starting at 150,000 KRW (specialized eye treatment)
Compared to some ordinary hyaluronic acid injection products on the market, Rejuran does come at a higher price point. However, its effectiveness, safety, and official certifications are far beyond what regular products can offer. Industry experts generally agree that Rejuran is a representative brand that “truly delivers premium quality that justifies its high price.”
V. Rejuran vs Other Hyaluronic Acid Serums: Why Is It the Top Choice?
With so many hyaluronic acid injection brands available on the market, including products from Filorga and Allergan, why has Rejuran managed to maintain its leading position for so long?
Comparison with Philoja
Filorga is a high-end French skincare brand renowned for its ability to Lifting skin’s firmness and elasticity. The cost per treatment typically starts at 400,000 KRW, placing it at a slightly higher price point than some of Rejuran’s product lines. However, Rejuran boasts deeper technical expertise in skin repair and regeneration, something that Filorga struggles to match.
Key Difference: Biological Regeneration vs. Filling
While most hyaluronic acid injections work by “replenishing Filler” to temporarily hydrate the skin, Rejuran’s PDRN technology activates the skin’s natural repair mechanisms, enabling it to “rebuild from within.” This approach yields more lasting results and brings positive long-term benefits to skin health. It is this fundamental technical difference that lies at the heart of Rejuran’s ability to maintain its position in the high-end market over time.

VI. Things You Need to Know Before Choosing Rejuran
1. You must choose a licensed medical facility.
Rejuran is a medical-grade product that requires treatment by licensed physicians in legitimate medical facilities across places like Taiwan and South Korea. With numerous counterfeit versions and unregulated sources available on the market, consumers must make sure to identify officially approved medical institutions to avoid health risks associated with using fake products or unprofessional treatments.
2. Number of Treatment Sessions and Effect Duration
It is generally recommended to undergo 3–5 sessions as part of the initial treatment course for Rejuran glow injection, with intervals of 2–4 weeks between sessions. Subsequent maintenance treatments can be done every 3–6 months, and the effects can last for half a year or even longer. Most people start to notice significant improvements in skin texture around 2–4 weeks after the first treatment.
3. Post-injection care
Within 24–48 hours after treatment, it’s important to avoid makeup, strenuous exercise, and exposure to high temperatures. Proper moisturization and sun protection are key to maximizing the effectiveness of the treatment.
Conclusion: Rejuran – a truly premium aesthetic medicine brand living up to its name
Based on this comprehensive analysis, Rejuran is a true premium beauty therapy brand—whether it’s in terms of technological sophistication, brand heritage, clinical certifications, or customer reviews, it represents the highest standard in the field of hyaluronic acid injections in South Korea. It isn’t just a label imposed by high prices; rather, it has built an unshakable brand advantage through solid biotechnological research and development along with rigorous clinical testing.
If you’re considering cosmetic hydration treatments in South Korea, Rejuran is definitely worth giving serious consideration. It’s recommended to first consult a reputable medical institution to understand your specific skin needs, so you can choose the product series that suits you best and ensure every penny spent yields the best results.
The content in this article is for reference only. Medical beauty treatments relate to personal health, so be sure to consult a licensed physician before making any decisions.
